Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594636 | 1.00 | MEN1 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL27983251 | 0.86 | MEN1 (0.70) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL31326827 | 0.83 | APP (0.46) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL5594806 | 0.78 | MAPT (0.62) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL5594804 | 0.78 | MAPT (0.62) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL687036 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL15659878 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL14964957 | 0.76 | MAPT (0.69) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL14964958 | 0.76 | MAPT (0.69) | MEN1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL687035 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |