Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964957 | 1.00 | MAPT (0.69) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL2681040 | 0.85 | MCL1 (0.54) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL4825046 | 0.85 | MCL1 (0.54) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL14965061 | 0.82 | ALDH1A1 (1.00) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL14965059 | 0.82 | ALDH1A1 (1.00) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL6229935 | 0.81 | MAPT (0.72) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL8631910 | 0.80 | RELA (0.59) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL8631913 | 0.80 | RELA (0.59) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL14306901 | 0.80 | MAPT (0.53) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL10053864 | 0.79 | APP (0.88) | MAPTALDH1A1RAB9AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |