Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.65 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457390 | 0.75 | EGFR (0.79) | EGFRMIFLCKKDM4EKMT2A | |
| SCHEMBL21457392 | 0.75 | EGFR (0.79) | EGFRMIFLCKKDM4EKMT2A | |
| SCHEMBL5594942 | 0.74 | MIF (0.51) | EGFRERBB2MIFLCKKDM4E | |
| SCHEMBL5595103 | 0.73 | EGFR (0.74) | EGFRERBB2KDM4EKMT2AALDH1A1 | |
| SCHEMBL10476374 | 0.73 | EGFR (0.63) | EGFRERBB2KDM4EKMT2AMAPK1 | |
| SCHEMBL5594247 | 0.73 | MAPT (0.60) | EGFRERBB2KDM4EKMT2AMAPK1 | |
| SCHEMBL29119411 | 0.71 | MIF (0.72) | EGFRMIFLCKKDM4EKMT2A | |
| SCHEMBL2985800 | 0.71 | EGFR (0.54) | EGFRERBB2KDM4EKMT2ACES2 | |
| SCHEMBL13916092 | 0.71 | EGFR (0.54) | EGFRERBB2KDM4EKMT2ACES2 | |
| SCHEMBL2985798 | 0.71 | EGFR (0.54) | EGFRERBB2KDM4EKMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |