Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5595297 | 0.99 | NAMPT (0.57) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL14524508 | 0.91 | NAMPT (0.50) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL8253777 | 0.89 | NAMPT (0.60) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL5388847 | 0.86 | NAMPT (0.58) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL10209845 | 0.84 | AURKA (0.52) | NAMPTMAPTAURKARPS6KB1CA1 | |
| SCHEMBL19694494 | 0.84 | NAMPT (0.62) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL14524512 | 0.84 | NAMPT (0.42) | NAMPTMAPTTDP1NPSR1XBP1 | |
| SCHEMBL3180689 | 0.83 | L3MBTL1 (0.61) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL15692011 | 0.83 | NAMPT (0.58) | NAMPTMAPTTDP1FPR3FPR2 | |
| SCHEMBL8245694 | 0.83 | CYP17A1 (0.54) | NAMPTMAPTTDP1FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208521-B2 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7049460-B1 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2006-05-23 | — | — | US | disclosed |
| US-20050215642-A1 | Selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1206447-B1 | SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS | WILEX AG (DE) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215642-A1 | Selective inhibitors of the urokinase plasminogen activator | PLAU, SERPINE1, PLAUR | NAMPT 1450/4885MAPT 3847/4885TDP1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.