SCHEMBL5595697

SCHEMBL5595697

[CH2]CCC(=O)[C@H](N)[C@H](C)CC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 14/20 0.42
DPP8 Q6V1X1 11/20 0.42
DPP9 Q86TI2 10/20 0.42
DPP7 Q9UHL4 9/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5595695 1.00 DPP4 (0.42) DPP4DPP8DPP9DPP7
SCHEMBL16173709 0.83 DPP4 (0.44) DPP4DPP8DPP9DPP7
SCHEMBL4996586 0.80 SLC7A5 (0.44) DPP4DPP8DPP9DPP7
SCHEMBL15233555 0.79 DPP4 (0.42) DPP4DPP8DPP9DPP7
SCHEMBL13934702 0.79 DPP4 (0.42) DPP4DPP8DPP9DPP7
SCHEMBL11139682 0.78 GABRP (0.33)
SCHEMBL23762426 0.78 DPP4 (0.47) DPP4DPP8DPP9DPP7
SCHEMBL13322716 0.78 DPP4 (0.47) DPP4DPP8DPP9DPP7
SCHEMBL12310505 0.78 DPP4 (0.47) DPP4DPP8DPP9DPP7
SCHEMBL18542711 0.78 DPP4 (0.47) DPP4DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833500-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION Biorunx Co., Ltd (KR) 2007-09-19 EP claimed
WO-2006065075-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION BIORUNX CO. LTD. (KR) 2006-06-22 WO claimed