Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571308 | 0.87 | — | — | |
| SCHEMBL5596457 | 0.83 | ALDH1A1 (0.34) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL5596690 | 0.77 | TP53 (0.32) | — | |
| SCHEMBL5596619 | 0.73 | PCSK9 (0.36) | — | |
| SCHEMBL1494198 | 0.72 | ALDH1A1 (0.37) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL5613562 | 0.70 | MAPK1 (0.33) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL19235527 | 0.68 | MAPK1 (0.32) | ALDH1A1ALOX15MAPK1 | |
| Biphenyl SCHEMBL27775455 | 0.68 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTMAPK1TDP1 | |
| SCHEMBL9499497 | 0.67 | MAPK1 (0.35) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL704260 | 0.67 | MAPK1 (0.36) | ALDH1A1ALOX15TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |