Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275234 | 0.93 | TSHR (0.55) | TSHRALDH1A1EPHX1THRBADH1B | |
| SCHEMBL16091260 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP2C19CYP1A2EPHX1 | |
| SCHEMBL14275233 | 0.87 | KDM4E (0.42) | TSHRALDH1A1CYP2C19CYP1A2KDM4E | |
| SCHEMBL8382688 | 0.87 | CA12 (0.50) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL28782488 | 0.86 | — | — | |
| SCHEMBL27253187 | 0.84 | KDM4E (0.47) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28323111 | 0.82 | — | — | |
| SCHEMBL21147761 | 0.82 | — | — | |
| SCHEMBL2362892 | 0.82 | ADRA1A (0.48) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12605236 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802700-A2 | LOW-VISCOSITY, RADIATION-CURABLE FORMULATION FOR PRODUCING ADAPTIVE EAR PIECES | Dreve Otoplastik GmbH (DE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006042514-A2 | LOW-VISCOSITY, RADIATION-CURABLE FORMULATION FOR PRODUCING ADAPTIVE EAR PIECES | DREVE OTOPLASTIK GMBH (DE) | 2006-04-27 | — | — | WO | disclosed |