Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596252 | 0.84 | SMN1; SMN2 (0.37) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5595954 | 0.84 | HTT (0.46) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596919 | 0.82 | NPC1 (0.46) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596579 | 0.81 | NPC1 (0.44) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596557 | 0.79 | NPC1 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596010 | 0.79 | NPC1 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596669 | 0.79 | NPC1 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL201692 | 0.79 | NPC1 (0.57) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5596200 | 0.78 | NPC1 (0.42) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28424598 | 0.78 | NPC1 (0.52) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |