Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 4/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596110 | 0.84 | NPC1 (0.42) | HTTTYRALOX5NPC1HPGD | |
| SCHEMBL5596611 | 0.82 | TYR (0.40) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL5596553 | 0.81 | TYR (0.39) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL5596404 | 0.79 | HTT (0.38) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL5596187 | 0.79 | HTT (0.40) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL5596040 | 0.79 | HTT (0.38) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL280118 | 0.79 | TYR (0.48) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL5596119 | 0.78 | HTT (0.37) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL28665182 | 0.77 | TYR (0.47) | SMN1; SMN2HTTMAPTALDH1A1TYR | |
| SCHEMBL29112780 | 0.77 | TYR (0.47) | SMN1; SMN2HTTMAPTALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |