Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596936 | 0.79 | HSD17B10 (0.48) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5596465 | 0.76 | HSD17B10 (0.46) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5596061 | 0.76 | PTPN22 (0.46) | PTPN22 | |
| SCHEMBL5596870 | 0.74 | PTPN22 (0.56) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5596217 | 0.73 | CYP1A2 (0.43) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5596711 | 0.73 | PTPN22 (0.50) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5605244 | 0.73 | CYP1A2 (0.50) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL15657172 | 0.70 | ALDH1A1 (0.38) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6405225 | 0.69 | HSD17B10 (0.78) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 | |
| SCHEMBL5596928 | 0.69 | PTPN22 (0.50) | HSD17B10CYP1A2CYP2C9CYP2C19PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |