Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861627 | 0.81 | PTPN22 (0.50) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3389391 | 0.80 | HSD17B10 (0.59) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23861443 | 0.79 | ESR1 (0.47) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5596944 | 0.78 | PTPN22 (0.50) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5596069 | 0.75 | HSD17B10 (0.67) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2221239 | 0.73 | PTPN22 (0.54) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1603439 | 0.73 | PTPN22 (0.54) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7296516 | 0.73 | PTPN22 (0.54) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20398800 | 0.73 | PTPN22 (0.54) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31356444 | 0.73 | PTPN22 (0.54) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |