SCHEMBL5596211

SCHEMBL5596211

CC(C)(C)c1ccc(O)c(C(P)(c2ccccc2)c2cc(C(C)(C)C)ccc2O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 1/20 0.50
CYP2D6 P10635 2/20 0.46
ESR1 P03372 4/20 0.46
ESR2 Q92731 3/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
TSHR P16473 3/20 0.42
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523323 0.86 ESR1 (0.58) ALDH1A1TDP1ALOX15HSD17B10HPGD
SCHEMBL11205966 0.82 ALDH1A1 (0.53) ALDH1A1TDP1ALOX15HSD17B10HPGD
SCHEMBL3895899 0.82 ALDH1A1 (0.53) ALDH1A1TDP1ALOX15HSD17B10HPGD
Benzene SCHEMBL28155736 0.81 ALDH1A1 (0.61) ALDH1A1TDP1ALOX15HSD17B10HPGD
SCHEMBL5596856 0.81 ESR1 (0.43) ALDH1A1TDP1ALOX15HSD17B10HPGD
SCHEMBL5596207 0.80 ALDH1A1 (0.59) ALDH1A1TDP1ALOX15HSD17B10HPGD
Phenol SCHEMBL6686964 0.79 ALDH1A1 (0.57) ALDH1A1TDP1ALOX15HSD17B10HPGD
Biphenyl SCHEMBL28011227 0.79 ALDH1A1 (0.53) ALDH1A1TDP1ALOX15HSD17B10HPGD
SCHEMBL11954771 0.79 ALDH1A1 (0.53) ALDH1A1TDP1ALOX15HSD17B10HPGD
Biphenyl SCHEMBL28492519 0.79 ALDH1A1 (0.53) ALDH1A1TDP1ALOX15HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed