Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196203 | 0.83 | CALM1 (0.50) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL18408878 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL11678015 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL4331683 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL11884686 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| Hydrochloric Acid SCHEMBL11571570 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL18425558 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| Hydrochloric Acid SCHEMBL11804664 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL31616701 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB | |
| Hydrochloric Acid SCHEMBL11571578 | 0.80 | CALM1 (0.47) | TSHRTDP1CALM1IDO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |