Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 4/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595960 | 0.76 | MEN1 (0.49) | PTPN22HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4138605 | 0.76 | PTPN22 (0.54) | RCE1PTPN22HSP90AA1HSD17B10CYP1A2 | |
| SCHEMBL5596420 | 0.76 | PTPN22 (0.54) | RCE1PTPN22HSP90AA1HSD17B10CYP1A2 | |
| SCHEMBL17540622 | 0.74 | PTPN22 (0.52) | RCE1PTPN22HSP90AA1HSD17B10LDHA | |
| SCHEMBL5596451 | 0.73 | HSD17B10 (0.56) | PTPN22HSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596446 | 0.73 | RCE1 (0.53) | RCE1PTPN22HSP90AA1HSD17B10CYP1A2 | |
| SCHEMBL7305915 | 0.72 | PTPN22 (0.54) | RCE1PTPN22HSP90AA1HSD17B10CYP1A2 | |
| SCHEMBL11374363 | 0.70 | TSHR (0.53) | RCE1PTPN22HSP90AA1LDHATSHR | |
| SCHEMBL18537228 | 0.70 | PTPN22 (0.47) | RCE1PTPN22HSP90AA1LDHAMAPT | |
| SCHEMBL8759057 | 0.70 | RCE1 (0.58) | RCE1PTPN22HSP90AA1LDHAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |