Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596420 | 0.79 | PTPN22 (0.54) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL4138605 | 0.79 | PTPN22 (0.54) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL17540622 | 0.78 | PTPN22 (0.52) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL11212117 | 0.77 | CYP2A6 (0.56) | PTPN22HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL5596446 | 0.76 | RCE1 (0.53) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL9749915 | 0.76 | RCE1 (0.61) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL7305908 | 0.75 | ALDH1A1 (0.44) | PTPN22HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL28513422 | 0.75 | RCE1 (0.59) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL11754689 | 0.74 | RCE1 (0.44) | PTPN22RCE1LDHAHSP90AA1HSD17B10 | |
| SCHEMBL11374363 | 0.73 | TSHR (0.53) | PTPN22RCE1LDHAHSP90AA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |