Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596241 | 0.90 | ALDH1A1 (0.34) | ALDH1A1MAPTHTTSMN1; SMN2TYR | |
| SCHEMBL5596014 | 0.87 | NPC1 (0.36) | HTTTYRTLR8HPGDCYP3A4 | |
| SCHEMBL5596187 | 0.83 | HTT (0.40) | ALDH1A1MAPTHTTSMN1; SMN2TYR | |
| SCHEMBL5596458 | 0.80 | NPC1 (0.39) | ALDH1A1MAPTHTTKDM4EHPGD | |
| SCHEMBL5596355 | 0.79 | TYR (0.36) | HTTTYRHPGDALOX5 | |
| SCHEMBL5596984 | 0.79 | TYR (0.37) | ALDH1A1MAPTHTTSMN1; SMN2TYR | |
| SCHEMBL5596428 | 0.77 | NPC1 (0.36) | HTTTYRTLR8HPGDCYP3A4 | |
| SCHEMBL5596553 | 0.76 | TYR (0.39) | ALDH1A1MAPTHTTSMN1; SMN2TYR | |
| SCHEMBL5596404 | 0.75 | HTT (0.38) | ALDH1A1MAPTHTTSMN1; SMN2TYR | |
| SCHEMBL5596040 | 0.75 | HTT (0.38) | ALDH1A1MAPTHTTSMN1; SMN2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |