Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596342 | 0.78 | GABRA1 (0.40) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5595970 | 0.78 | GABRA1 (0.40) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596434 | 0.77 | CYP3A4 (0.56) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596998 | 0.72 | TDP1 (0.50) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596070 | 0.72 | TDP1 (0.50) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596096 | 0.72 | CYP3A4 (0.50) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596312 | 0.71 | TDP1 (0.43) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL18224 | 0.69 | CYP3A4 (1.00) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5596891 | 0.69 | TDP1 (0.46) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11020186 | 0.67 | CYP3A4 (0.93) | CYP3A4TSHRTDP1GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |