SCHEMBL5596768

SCHEMBL5596768

O=[N+]([O-])c1cc2c(c([N+](=O)[O-])c1)[S+]([O-])c1ccccc1C2[N+](=O)[O-]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.40
▸ TSHR P16473 2/20 0.40
▸ MEN1 O00255 6/20 0.35
▸ KMT2A Q03164 6/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ ALDH1A1 P00352 8/20 0.35
▸ MAPT P10636 3/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ LMNA P02545 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ MITF O75030 1/20 0.35
▸ HPGD P15428 2/20 0.33
▸ GPR35 Q9HC97 2/20 0.33
▸ HIF1A Q16665 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304593 0.71 TDP1 (0.41) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL74684 0.68 TSHR (0.39) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL11664480 0.64 TDP1 (0.42) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL15153603 0.62 ALDH1A1 (0.42) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL30985282 0.61 ALDH1A1 (0.39) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL1306347 0.61 ALDH1A1 (0.39) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL30522666 0.59 TSHR (0.56) TDP1TSHRMEN1KMT2AALDH1A1
SCHEMBL5958789 0.59 HSP90AA1 (0.59) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL31220888 0.59 TSHR (0.56) TDP1TSHRMEN1KMT2AALDH1A1
SCHEMBL6142061 0.58 ALDH1A1 (0.34) TSHRMEN1KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 — — EP claimed
EP-0486038-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1996-10-16 — — EP claimed
US-5213924-A Copolymers, improved mechanical strength, hardness IDEMITSU KOSAN CO. LTD. (JP) 1993-05-25 — — US claimed
EP-0486038-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-05-20 — — EP claimed
US-7297449-B2 Optical recording medium and optical recording apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2007-11-20 — — US disclosed
US-20060257748-A1 Optical recording medium and optical recording apparatus TSUKAMOTO TAKAYUKI 2006-11-16 — — US disclosed
US-7060393-B2 Optical recording medium and optical recording apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2006-06-13 — — US disclosed
EP-0785477-B1 Electrophotographic photoreceptor, image forming apparatus and use of this photoreceptor in an image forming process FUJI XEROX CO LTD (JP) 2004-04-14 — — EP disclosed
US-20020197538-A1 Optical recording medium and optical recording apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2002-12-26 — — US disclosed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 — — EP disclosed
EP-0597128-B1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN CO (JP) 1999-09-15 — — EP disclosed
US-5800950-A MULTILAYER OPTICAL RECORDING MEDIA WITH CHARGE GENERATING AND CHARGE TRANSPORTING MATERIAL FOR ELECTROOPTICAL EFFECT KABUSHIKI KAISHA TOSHIBA (JP) 1998-09-01 — — US disclosed
US-5506331-A POLYESTER OR POLYCARBONATE HAVING HYDRAZONE STRUCTURE IN REPEATING UNITS, USABLE AS CHARGE TRANSPORT MATERIAL OR BINDER RESIN IN CHARGE TRANSPORT LAYER IDEMITSU KOSAN CO., LTD. (JP) 1996-04-09 — — US disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 — — EP disclosed
EP-0597128-A1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-05-18 — — EP disclosed
EP-0582722-A1 POLYCARBONATE POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-16 — — EP disclosed
US-5213924-A Copolymers, improved mechanical strength, hardness IDEMITSU KOSAN CO. LTD. (JP) 1993-05-25 — — US disclosed
EP-0486038-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-05-20 — — EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 — — EP disclosed
US-4985326-A PHOTOSENSITIVE LAYER CONTAINING A POLYCARBONATE AS BINDER RESIN IDEMITSU KOSAN CO., LTD. (JP) 1991-01-15 — — US disclosed
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