Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | DNM2 | P50570 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960367 | 0.79 | EGFR (0.44) | CYP2C19EGFRMKNK1DNM2HRH3 | |
| SCHEMBL11463729 | 0.72 | CYP2C19 (0.43) | CYP2C19MKNK1DNM2HRH3HRH4 | |
| SCHEMBL13733509 | 0.72 | HRH3 (0.47) | CYP2C19EGFRMKNK1DNM2HRH3 | |
| SCHEMBL12633603 | 0.72 | CYP2C19 (0.43) | CYP2C19EGFRMKNK1DNM2HRH3 | |
| SCHEMBL5596454 | 0.71 | CYP2C19 (0.44) | CYP2C19MKNK1DNM2HRH3HRH4 | |
| SCHEMBL933805 | 0.69 | CYP2C19 (0.44) | CYP2C19MKNK1DNM2HRH3HRH4 | |
| SCHEMBL21513657 | 0.69 | IGF1R (0.44) | — | |
| SCHEMBL5622381 | 0.69 | ALDH1A1 (0.62) | CYP2C19MKNK1DNM2HRH3HRH4 | |
| SCHEMBL5505032 | 0.68 | EGFR (0.53) | EGFRMKNK1DNM2HRH3P2RX3 | |
| SCHEMBL24218536 | 0.68 | HDAC3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |