SCHEMBL5597110

SCHEMBL5597110

c1ccc(P(c2ccccc2)c2ncccc2-c2cccnc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.47
ALDH1A1 P00352 4/20 0.45
PTGS2 P35354 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
KCNA5 P22460 1/20 0.44
CYP11B1 P15538 2/20 0.42
ALOX5 P09917 1/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 1/20 0.42
HSD17B10 Q99714 3/20 0.41
HPGD P15428 2/20 0.41
NPY5R Q15761 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CYP19A1 P11511 1/20 0.41
MAPT P10636 2/20 0.41
CYP11B2 P19099 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22471745 0.88 CYP2A6 (0.46) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL28610467 0.88 KDM4E (0.48) CYP2A6ALDH1A1PTGS2CYP3A4KDM4E
SCHEMBL5597112 0.84 CYP2A6 (0.45) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL22471744 0.80 CYP2A6 (0.50) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL4621666 0.76 CYP2A6 (0.64) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL31017586 0.76 CYP2A6 (0.64) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL30026143 0.75 CYP2A6 (0.70) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL20541087 0.75 CYP2A6 (0.70) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL31038075 0.75 PTGS2 (0.56) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4
SCHEMBL21305225 0.74 CYP11B1 (0.44) CYP2A6ALDH1A1PTGS2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746037-A Synthetic method of alpha-halogenated borate compound and product thereof 同济大学 2023-03-07 CN claimed
CN-111417618-B Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides 先正达参股股份有限公司 2023-06-30 CN disclosed
CN-115746037-A Synthetic method of alpha-halogenated borate compound and product thereof 同济大学 2023-03-07 CN disclosed
CN-113557227-A Method for producing prostaglandin 协和医药化工股份有限公司 2021-10-26 CN disclosed
CN-111417618-A Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides 先正达参股股份有限公司 2020-07-14 CN disclosed
EP-1858644-A2 METHOD FOR ASYMMETRIC HYDROSILYLATION OF KETONES The Hong Kong Polytechnic University (CN) 2007-11-28 EP disclosed
WO-2006089129-A2 METHOD FOR ASYMMETRIC HYDROSILYLATION OF KETONES THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2006-08-24 WO disclosed