Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659231 | 0.84 | HPGD (0.66) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL16339283 | 0.84 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL9836159 | 0.84 | CDK4 (0.49) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL9836151 | 0.84 | CDK4 (0.49) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL10509104 | 0.80 | LIG1 (0.53) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8025735 | 0.78 | HPGD (0.46) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL14030730 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL8025732 | 0.78 | HPGD (0.46) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL3793697 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2TSHR | |
| SCHEMBL4384402 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175025-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-19 | — | — | WO | disclosed |
| EP-1215254-B1 | Radiation-curable organopolysiloxane composition | SHINETSU CHEMICAL CO (JP) | 2007-08-29 | — | — | EP | disclosed |