Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 6/20 | 0.75 |
| ▸ | RORC | P51449 | 5/20 | 0.75 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.75 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.75 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.65 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.63 |
| ▸ | CRYAB | P02511 | 1/20 | 0.62 |
| ▸ | HMGCR | P04035 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGAV | P06756 | 1/20 | 0.62 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.62 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL5597221 | 1.00 | OSBP (0.75) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21182320 | 0.91 | OSBP (0.75) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21182319 | 0.91 | OSBP (0.75) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL162271 | 0.91 | OSBP (0.75) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL28201162 | 0.89 | OSBP (0.80) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL27942138 | 0.89 | OSBP (0.96) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL31139886 | 0.88 | OSBP (0.73) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL4730755 | 0.88 | OSBP (0.88) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL1369757 | 0.88 | OSBP (0.91) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL19460298 | 0.88 | OSBP (0.91) | OSBPRORCOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980203-B1 | ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES | SQUIRES MERYL (US) | 2007-04-04 | — | — | EP | disclosed |