SCHEMBL5597375

SCHEMBL5597375

Cc1ccc(S(=O)(=O)O)c(-c2ccccc2Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
ELANE P08246 1/20 0.44
MAOA P21397 2/20 0.41
MAPT P10636 5/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
F2 P00734 2/20 0.38
MPL P40238 1/20 0.37
EPHX2 P34913 1/20 0.37
PGAM1 P18669 1/20 0.36
NFKB1 P19838 2/20 0.36
MYC P01106 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
HDAC7 Q8WUI4 1/20 0.36
KMT2A Q03164 2/20 0.35
HTT P42858 2/20 0.35
XBP1 P17861 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3885120 0.83 ELANE (0.47) ELANEMAPTALDH1A1KDM4EF2
SCHEMBL7857421 0.82 ELANE (0.46) MAOBELANEMAOAMAPTALDH1A1
SCHEMBL9131035 0.81 ELANE (0.44) MAOBELANEMAPTALDH1A1KDM4E
SCHEMBL780160 0.81 ELANE (0.44) ELANEMAPTALDH1A1KDM4EF2
SCHEMBL8820520 0.81 PTGDR2 (0.47) MAOBELANEMAPTALDH1A1KDM4E
SCHEMBL25266704 0.81 ELANE (0.49) MAOBELANEMAOAMAPTALDH1A1
SCHEMBL2516098 0.81 ELANE (0.44) MAOBELANEMAOAMAPTALDH1A1
SCHEMBL10698758 0.78 MAOA (0.48) MAOBELANEMAOAMAPTALDH1A1
SCHEMBL3151094 0.78 HDAC7 (0.49) MAOBELANEMAPTALDH1A1KDM4E
SCHEMBL18240867 0.77 ELANE (0.41) ELANEALDH1A1KMT2ALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970937-B1 POLYMER GEL AND PROCESS FOR THE ACTIVATION OF ACTIVE HYDROGEN COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2007-07-04 EP disclosed
US-7094853-B2 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 2006-08-22 US disclosed
US-6914155-B2 High polymer gel and activation method for compounds containing active hydrogen NIPPON SHOKUBAI CO., LTD. (JP) 2005-07-05 US disclosed
US-20040087727-A1 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. 2004-05-06 US disclosed
US-6646083-B2 Such as diallyldimethylammonium chloride crosslinked with 1,3-bis(N,N-diallylpiperid-1-ium-4-yl) propane dichloride; thermal stability; use as polymer catalyst for producing glycols from oxiranes; ion exchange catalyst NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-11 US disclosed
US-20020028887-A1 Crosslinked polymer, method for manufacturing it and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 2002-03-07 US disclosed
US-20020028872-A1 High polymer gel and activation method for compounds containing active hydrogen NIPPON SHOKUBAI CO., LTD. 2002-03-07 US disclosed
EP-1022058-A1 METHOD FOR ACTIVATING ACTIVE HYDROGEN AND ACTIVATION CATALYST Nippon Shokubai Co., Ltd. (JP) 2000-07-26 EP disclosed
EP-0970937-A1 POLYMER GEL AND PROCESS FOR THE ACTIVATION OF ACTIVE HYDROGEN COMPOUNDS Nippon Shokubai Co., Ltd. (JP) 2000-01-12 EP disclosed