SCHEMBL5597629

SCHEMBL5597629

C=C(C)C(=O)C(N)(CN)C(=O)C(=C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28805724 0.81 TDP1 (0.36) TDP1
SCHEMBL17239823 0.80 TDP1 (0.39) TDP1
SCHEMBL2184778 0.75 TDP1 (0.39) TDP1KDM4E
SCHEMBL27935190 0.75 TDP1 (0.39) TDP1KDM4E
SCHEMBL283186 0.73 KDM4E (0.35) TDP1KDM4E
SCHEMBL31295695 0.72 ODC1 (0.38) KDM4E
SCHEMBL29962193 0.72 TDP1 (0.32) TDP1
SCHEMBL12962523 0.70
SCHEMBL10456199 0.70 FFAR3 (0.31) TDP1KDM4E
SCHEMBL27734495 0.70 TDP1 (0.35) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102365262-B Hydrophobic monomers, hydrophobically derivatized supports, and methods of making and using the same 3M INNOVATIVE PROPERTIES CO 2014-09-17 CN disclosed
EP-1794213-A1 SUBSTRATE WITH ATTACHED DENDRIMERS 3M Innovative Properties Company (US) 2007-06-13 EP disclosed
WO-2006039052-A1 SUBSTRATE WITH ATTACHED DENDRIMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-13 WO disclosed
US-6379599-B1 Process for the preparation of molecularly imprinted polymers useful for separation of enzymes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-30 US disclosed
EP-0556271-A1 BIOLOGICAL ACTIVE MATERIAL COVALENTLY IMMOBILIZED ON TO AZLACTONE-FUNCTIONAL POLYMERIC SUPPORTS AND METHOD FOR PREPARING IT. MINNESOTA MINING & MFG (US) 1993-08-25 EP disclosed