SCHEMBL2184778

SCHEMBL2184778

C=C(C)C(=O)C(O)(CN)C(=O)C(=C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27935190 0.75 TDP1 (0.39) TDP1KDM4E
SCHEMBL5597629 0.75 TDP1 (0.39) TDP1KDM4E
SCHEMBL27734495 0.75 TDP1 (0.35) TDP1
SCHEMBL2638864 0.73 TDP1 (0.32) TDP1
SCHEMBL22445222 0.73 TDP1 (0.32) TDP1
SCHEMBL2142716 0.73 KDM4E (0.35) TDP1KDM4E
SCHEMBL28041101 0.70 TDP1 (0.35) TDP1KDM4E
SCHEMBL5507567 0.67 TDP1 (0.40) TDP1
SCHEMBL28805724 0.67 TDP1 (0.36) TDP1
SCHEMBL27886468 0.65 HMGCR (0.36) TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-12 US claimed
EP-2342247-A1 METHOD FOR PREPARING MOLECULAR IMPRINT POLYMERS (PEM) BY RADICAL POLYMERISATION Universite De Technologie De Compiegne - UTC (FR) 2011-07-13 EP claimed
WO-2010026308-A1 METHOD FOR PREPARING MOLECULAR IMPRINT POLYMERS (PEM) BY RADICAL POLYMERISATION UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE - UTC (FR) 2010-03-11 WO claimed
US-10772823-B2 Molecularly imprinted polymer for selectively trapping odorous molecules L'OREAL (FR) 2020-09-15 US disclosed
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-12 US disclosed
EP-2342247-A1 METHOD FOR PREPARING MOLECULAR IMPRINT POLYMERS (PEM) BY RADICAL POLYMERISATION Universite De Technologie De Compiegne - UTC (FR) 2011-07-13 EP disclosed
WO-2010026308-A1 METHOD FOR PREPARING MOLECULAR IMPRINT POLYMERS (PEM) BY RADICAL POLYMERISATION UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE - UTC (FR) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10772823-B2 Molecularly imprinted polymer for selectively trapping odorous molecules OR10J3, OR51E2, MSMO1 TDP1 2821/4885KDM4E 3113/4885
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OR10J3, OR51E2, MSMO1 TDP1 2821/4885KDM4E 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.