SCHEMBL5597632

SCHEMBL5597632

NC(CCOP(=O)(Oc1ccccc1)Oc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.46
LAP3 P28838 2/20 0.46
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LTA4H P09960 1/20 0.44
KIF11 P52732 3/20 0.43
GRIK1 P39086 1/20 0.42
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19534616 0.84 ANPEP (0.45) ANPEPLAP3ALPIPKMPTGS1
SCHEMBL2678810 0.84 ELANE (0.44) ANPEPLAP3LTA4H
Triphenyl Phosphate SCHEMBL694133 0.80 ANPEP (0.46) ANPEPLAP3POLBKMT2ATDP1
SCHEMBL56342 0.78 POLB (0.50) ANPEPLAP3POLBKMT2ATDP1
SCHEMBL343402 0.78 SRC (0.52) KMT2ATDP1PKM
Serine SCHEMBL19520734 0.78 P2RY10 (0.46)
SCHEMBL15201180 0.78 ANPEP (0.46) ANPEPLAP3KMT2ATDP1PKM
SCHEMBL9090603 0.77 LTA4H (0.53) TDP1LTA4HKIF11ALPIPKM
SCHEMBL5082950 0.77 LTA4H (0.53) TDP1LTA4HKIF11ALPIPKM
SCHEMBL5082944 0.77 LTA4H (0.53) TDP1LTA4HKIF11ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091928-B1 NOVEL ACYL PSEUDODIPEPTIDES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME OM PHARMA (CH) 2007-02-28 EP disclosed
EP-1091928-A1 NOVEL ACYL PSEUDODIPEPTIDES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME OM Pharma (CH) 2001-04-18 EP disclosed
WO-2000000462-A1 NOVEL ACYL PSEUDODIPEPTIDES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME OM PHARMA (CH) 2000-01-06 WO disclosed