Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.65 |
| ▸ | HTR1A | P08908 | 8/20 | 0.57 |
| ▸ | HTR1D | P28221 | 8/20 | 0.57 |
| ▸ | HTR1B | P28222 | 8/20 | 0.57 |
| ▸ | HTR2C | P28335 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | HTR7 | P34969 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | HTR1E | P28566 | 2/20 | 0.57 |
| ▸ | HTR1F | P30939 | 2/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972094 | 0.79 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6974970 | 0.78 | HTR6 (0.72) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6970959 | 0.76 | HTR6 (0.81) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6973905 | 0.76 | HTR6 (0.87) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6977609 | 0.76 | HTR6 (0.72) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6977605 | 0.75 | HTR6 (0.67) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6972493 | 0.75 | HTR6 (0.83) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6970866 | 0.75 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6972553 | 0.75 | HTR6 (0.79) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6975625 | 0.75 | HTR6 (0.78) | HTR6HTR1AHTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799306-A2 | COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DISORDERS | F. Hoffmann-Roche AG (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006037482-A2 | COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-13 | — | — | WO | claimed |