Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597784 | 0.90 | HIF1A (0.46) | HIF1AKMT2AALDH1A1TSHRHSP90AB1 | |
| SCHEMBL5597653 | 0.86 | HIF1A (0.44) | HIF1AKMT2AALDH1A1 | |
| SCHEMBL29765456 | 0.84 | HIF1A (0.60) | HIF1AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL3311081 | 0.84 | HIF1A (0.60) | HIF1AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL3621124 | 0.84 | HIF1A (0.60) | HIF1AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL29765448 | 0.84 | HIF1A (0.60) | HIF1AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL5597636 | 0.82 | ALDH1A1 (0.47) | HIF1AKMT2AALDH1A1TSHRLMNA | |
| SCHEMBL5597746 | 0.81 | ALDH1A1 (0.36) | KMT2AALDH1A1TSHRHSP90AB1LMNA | |
| SCHEMBL3625146 | 0.80 | HIF1A (0.47) | HIF1AKMT2AALDH1A1TSHRLMNA | |
| SCHEMBL3625149 | 0.80 | HIF1A (0.47) | HIF1AKMT2AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765304-B2 | METHOD OF PREPARING ALPHA-METHOXYIMINOCARBOXYLIC ACID METHYLAMIDES, AND INTERMEDIATES USED IN THE METHOD | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | claimed |