Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161427 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL5154438 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL10685650 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL5571899 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL4373552 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL17770677 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL8218531 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL7653269 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| SCHEMBL11219189 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1TSHRCYP2D6BLM | |
| Hydrochloric Acid SCHEMBL28609742 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TSHRCYP2D6BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189622-B1 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GENZYME CORP (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1014999-B1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GENZYME CORP (US) | 2004-12-08 | — | — | EP | claimed |
| JP-2002544226-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1189622-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | Geltex Pharmaceuticals, Inc. (US) | 2002-03-27 | — | — | EP | claimed |
| WO-2000069428-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 2000-11-23 | — | — | WO | claimed |
| EP-1014999-A1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 2000-07-05 | — | — | EP | claimed |
| WO-1999015186-A1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-04-01 | — | — | WO | claimed |
| US-20160220512-A1 | MODIFIED RELEASE PHARMACEUTICAL FORMULATIONS | RUBICON RES PRIVATE LTD (IN) | 2016-08-04 | — | — | US | disclosed |
| EP-1800686-A2 | Anionic polymers as toxin binders and antibacterial agents | GENZYME CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| US-4256903-A | REACTING SULFUR DIOXIDE AND CONJUGATED DIENES IN THE PRESENCE OF A MONO OR DI-ALKENYL AMINE | PHILLIPS PETROLEUM COMPANY (US) | 1981-03-17 | — | — | US | disclosed |