Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832946 | 1.00 | SLC6A2 (0.47) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL11862878 | 0.94 | SLC6A2 (0.42) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL11862882 | 0.94 | SLC6A2 (0.42) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL11862186 | 0.93 | SLC6A2 (0.41) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL11630014 | 0.84 | MAOB (0.42) | SLC6A2TAAR1CYP2D6TRPA1CYP1A2 | |
| SCHEMBL11630017 | 0.84 | MAOB (0.42) | SLC6A2TAAR1CYP2D6TRPA1CYP1A2 | |
| SCHEMBL4835685 | 0.81 | SLC6A4 (0.50) | SLC6A2TAAR1LMNACYP2D6CYP1A2 | |
| SCHEMBL3832287 | 0.78 | SLC6A2 (0.59) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL28558348 | 0.77 | SLC6A2 (0.52) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL5784144 | 0.77 | SLC6A2 (0.52) | SLC6A2TAAR1LMNACYP2D6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268262-B2 | Method for recovering trans-1,2-dichloroethene | PPG INDUSTRIES OHIO, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| EP-1740519-A1 | METHOD FOR RECOVERING TRANS-1,2-DICHLOROETHENE | PPG Industries Ohio, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005110954-A1 | METHOD FOR RECOVERING TRANS-1,2-DICHLOROETHENE | PPG INDUSTRIES OHIO, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050245775-A1 | Method for recovering trans-1,2-dichloroethene | EAGLE US 2 LLC | 2005-11-03 | — | — | US | disclosed |
| EP-1521732-A1 | METHOD OF STABILIZING TRICHLOROETHANE DURING PRODUCTION | PPG Industries Ohio, Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20040030203-A1 | Method of stabilizing trichloroethane during production | PPG INDUSTRIES OHIO, INC. | 2004-02-12 | — | — | US | disclosed |
| WO-2004007409-A1 | METHOD OF STABILIZING TRICHLOROETHANE DURING PRODUCTION | PPG INDUSTRIES OHIO, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| US-6150573-A | Concurrent production of trichloroethane isomers | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-5731482-A | Method for purifying perchloroethylene containing dichlorobutadiene | PPG INDUSTRIES, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5315052-A | Concurrent production of trichloroethane isomers | PPG INDUSTRIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5298646-A | Introducing molecular chlorine to stripping zone, contacting ethyl chloroformate in rectifying zone, condensation, refluxing, removal of gaseous phase | PPG INDUSTRIES, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5051536-A | Using a free radical catalyst to form cis-, trans-isomers | PPG INDUSTRIES, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| WO-1991002708-A1 | METHOD FOR ISOMERIZING 1,2-DICHLOROETHENE | PPG INDUSTRIES, INC. (US) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030203-A1 | Method of stabilizing trichloroethane during production | TTPA, CBR1, TCEA1 | SLC6A2 4638/4885TAAR1 320/4885LMNA 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.