Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15261996 | 0.92 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5598086 | 0.88 | KDM4E (0.61) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5591509 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL15262169 | 0.81 | KDM4E (0.48) | SMN1; SMN2KDM4EALDH1A1HPGDCCNA2 | |
| SCHEMBL15261476 | 0.81 | KDM4E (0.60) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL902729 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14033028 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5597896 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5591506 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5597985 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028434-A1 | NOVEL PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-15 | — | — | WO | disclosed |