Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598233 | 0.93 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5597861 | 0.93 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5591467 | 0.92 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5598255 | 0.91 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5598520 | 0.90 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5597917 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5597501 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5598019 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5591286 | 0.84 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5597985 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028434-A1 | NOVEL PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-15 | — | — | WO | disclosed |