Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208361 | 0.85 | HRH3 (0.69) | HRH3 | |
| SCHEMBL7196914 | 0.85 | HRH3 (0.61) | HRH3GAASMN1; SMN2 | |
| SCHEMBL5202473 | 0.85 | HRH3 (1.00) | HRH3GAASMN1; SMN2CCR3ALDH1A1 | |
| SCHEMBL7179046 | 0.83 | HRH3 (0.62) | HRH3KCNH2GAASMN1; SMN2 | |
| SCHEMBL5202813 | 0.83 | HRH3 (0.71) | HRH3KCNH2SMN1; SMN2 | |
| SCHEMBL5598262 | 0.82 | HRH3 (0.74) | HRH3KCNH2GAASMN1; SMN2CCR3 | |
| SCHEMBL5202705 | 0.76 | HRH3 (1.00) | HRH3GAASMN1; SMN2 | |
| SCHEMBL13463052 | 0.74 | HRH3 (0.70) | HRH3GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9013903 | 0.73 | SMN1; SMN2 (0.58) | HRH3GAASMN1; SMN2 | |
| SCHEMBL14159067 | 0.72 | HRH3 (0.70) | HRH3GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241778-B2 | Non-imidazole aryloxypiperidines | ORTHO MCNEIL PHARMACEUTICAL, INC (US) | 2007-07-10 | — | — | US | claimed |