Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614277 | 0.84 | SLC18A2 (0.44) | SLC18A2CHRNB2CHRNA4KCNH2CHRNA5 | |
| SCHEMBL2691261 | 0.77 | SLC18A2 (0.70) | SLC18A2 | |
| SCHEMBL27118538 | 0.76 | HTR2A (0.42) | KCNH2 | |
| SCHEMBL609099 | 0.75 | HRH3 (0.60) | HRH3 | |
| SCHEMBL610317 | 0.75 | SIGMAR1 (0.54) | HRH3KCNH2 | |
| SCHEMBL609873 | 0.74 | HRH3 (0.59) | HRH3 | |
| SCHEMBL818365 | 0.74 | HRH3 (0.59) | HRH3 | |
| SCHEMBL13456530 | 0.74 | CYP4F2 (0.36) | — | |
| SCHEMBL9963995 | 0.73 | SLC18A2 (0.68) | SLC18A2 | |
| SCHEMBL11447497 | 0.72 | HRH3 (0.49) | HRH3CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7222650-B2 | Tire with a tread comprising a rubbery polymer of a functionalized monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-6995224-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6936669-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-6933358-B2 | Reacting secordary amine with 2,3-dihalopropene forming monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050131181-A1 | FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | SLC18A2 3734/4885HRH3 263/4885CHRNB4 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.