Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668334 | 0.81 | IKBKB (0.47) | KDM4EGPR3EGFRCYP1A2PLAU | |
| SCHEMBL422040 | 0.81 | IKBKB (0.47) | KDM4EGPR3EGFRCYP1A2PLAU | |
| SCHEMBL27808756 | 0.79 | IKBKB (0.46) | KDM4EGPR3EGFRCYP1A2PLAU | |
| Hydrochloric Acid SCHEMBL14843117 | 0.79 | IKBKB (0.46) | KDM4EGPR3EGFRCYP1A2PLAU | |
| SCHEMBL10559629 | 0.78 | IKBKB (0.41) | KDM4EGPR3EGFRCYP1A2PLAU | |
| SCHEMBL2005662 | 0.77 | MGAM (0.41) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL28127066 | 0.77 | CYP1A2 (0.37) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL29427872 | 0.74 | MGAM (0.50) | KDM4EGPR3EGFRALDH1A1MAPT | |
| SCHEMBL5350724 | 0.74 | MGAM (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL2337793 | 0.74 | MGAM (0.50) | KDM4EGPR3EGFRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797002-B | Dyrk1 inhibitors and uses thereof | 迪亚克森海特公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103797002-B | Dyrk1 inhibitors and uses thereof | 迪亚克森海特公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2744797-A1 | DYRK1 INHIBITORS AND USES THEREOF | Diaxonhit (FR) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013026806-A1 | DYRK1 INHIBITORS AND USES THEREOF | EXONHIT SA (FR) | 2013-02-28 | — | — | WO | disclosed |
| WO-2007072041-A1 | THERAPEUTIC COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |