Sugi Predict

Sugi Predict / Compounds / SCHEMBL29427872

SCHEMBL29427872

SCHEMBL29427872

O=C(O)c1ncc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 2/20 0.50
▸ ALDH1A1 P00352 4/20 0.48
▸ HPGD P15428 1/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MAPT P10636 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ CNR2 P34972 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GPR3 P46089 1/20 0.41
▸ EGFR P00533 1/20 0.41
▸ RAB9A P51151 2/20 0.40
▸ MAP3K5 Q99683 1/20 0.40
▸ HCAR2 Q8TDS4 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ GPBAR1 Q8TDU6 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337793 1.00 MGAM (0.50) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL30824218 0.87 MGAM (0.42) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL5350724 0.84 MGAM (0.42) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL31317518 0.83 CNR2 (0.54) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL27822677 0.83 CNR2 (0.54) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL2005662 0.82 MGAM (0.41) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL31325746 0.82 MAP3K5 (0.46) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL4906407 0.82 MAP3K5 (0.46) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL16506805 0.82 RAB9A (0.41) MGAMALDH1A1HPGDALOX15HSD17B10
SCHEMBL422040 0.82 IKBKB (0.47) MGAMALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 — — US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 — — EP disclosed
US-12317909-B2 Methods for removing bitter taste from liquid beverages PARISH JR WILLIAM L (US) 2025-06-03 — — US disclosed
CN-119859121-A Preparation method of quinic acid compound 北京颖泰嘉和生物科技股份有限公司 2025-04-22 — — CN disclosed
US-20250008987-A1 SYSTEMS AND METHODS FOR REMOVING BITTER TASTE FROM LIQUID BEVERAGES PARISH JR WILLIAM L (US) 2025-01-09 — — US disclosed
CN-119161332-A Raltitrexed degrading impurity and preparation method thereof 无锡紫杉药业股份有限公司 2024-12-20 — — CN disclosed
CN-119161331-A Preparation method of degradation impurities in raltitrexed preparation 浙江皓格药业有限公司 2024-12-20 — — CN disclosed
CN-119161333-A Fine drying bag purification method of raltitrexed 无锡紫杉药业股份有限公司 2024-12-20 — — CN disclosed
CN-119060033-A Raltitrexed degrading impurity and preparation method thereof 无锡紫杉药业股份有限公司 2024-12-03 — — CN disclosed
CN-117903125-A Preparation method of raltitrexed 无锡紫杉药业股份有限公司 2024-04-19 — — CN disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 — — WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 — — EP disclosed
CN-114615890-B Herbicidal mixtures comprising aminopyridine and quinic acid 安道麦阿甘有限公司 2024-02-13 — — CN disclosed
CN-117327060-A Preparation method of intermediate impurity of raltitrexed 无锡紫杉药业股份有限公司 2024-01-02 — — CN disclosed
CN-116507327-A Chewable formulations 礼蓝动物保健有限公司 2023-07-28 — — CN disclosed
EP-4142513-A1 SYSTEMS AND METHODS FOR REMOVING BITTER TASTE FROM LIQUID BEVERAGES Parish, Jr., William L. (US) 2023-03-08 — — EP disclosed
US-20220251109-A1 OXAAZAQUINAZOLINE-7(8H)-KETONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) 2022-08-11 — — US disclosed
CN-114805311-A Spirocyclic indenes 苏州亚盛药业有限公司 2022-07-29 — — CN disclosed
WO-2022068921-A1 QUINAZOLINE COMPOUND AND APPLICATION THEREOF 上海医药集团股份有限公司 2022-04-07 — — WO disclosed
EP-3964516-A1 OXAAZAQUINAZOLINE-7(8H)-KETONE COMPOUND, PREPARATION METHOD THERFOR AND PHARMACEUTICAL APPLICATION THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2022-03-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251109-A1 OXAAZAQUINAZOLINE-7(8H)-KETONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF KRAS, NRAS, WEE1 MGAM 2245/4885ALDH1A1 269/4885HPGD 271/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL MGAM 157/4885ALDH1A1 4390/4885HPGD 4694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.