Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21618584 | 0.75 | CYP2D6 (0.33) | HSD11B1 | |
| SCHEMBL12039769 | 0.73 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL1555235 | 0.72 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL24554753 | 0.72 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL21618645 | 0.69 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL20803862 | 0.69 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL12546726 | 0.67 | — | — | |
| SCHEMBL26050253 | 0.67 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL24841889 | 0.66 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL24107346 | 0.66 | PDCD1 (0.36) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |