⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212972 | 1.00 | — | — | |
| SCHEMBL6681701 | 0.86 | THRB (0.32) | — | |
| SCHEMBL22570751 | 0.84 | — | — | |
| SCHEMBL10654503 | 0.84 | — | — | |
| SCHEMBL2452406 | 0.84 | THRB (0.30) | — | |
| SCHEMBL24587061 | 0.84 | MEN1 (0.43) | — | |
| SCHEMBL24587092 | 0.84 | MEN1 (0.43) | — | |
| SCHEMBL17594435 | 0.83 | MEN1 (0.38) | — | |
| SCHEMBL8742318 | 0.81 | — | — | |
| SCHEMBL24611418 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154247-A1 | STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF | 江苏豪森药业集团有限公司 | 2019-08-15 | — | — | WO | disclosed |
| EP-1807070-A1 | COMBINATIONS OF SUBSTITUTED AZETIDINONES AND CB1 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006039334-A1 | COMBINATIONS OF SUBSTITUTED AZETIDONONES AND CB1 ANTAGONISTS | SCHERING CORPORATION (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060069080-A1 | Combinations of substituted azetidinones and CB1 antagonists | SCHERING CORPORATION | 2006-03-30 | — | — | US | disclosed |
| EP-0868420-B1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI SYNTHELABO (FR) | 2000-03-29 | — | — | EP | disclosed |
| EP-0885889-A2 | Process for the preparation of pyrazole-3-carboxylic acids | SANOFI (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0868420-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997021682-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1997-06-19 | — | — | WO | disclosed |
| US-5624941-A | Pyrazole derivatives, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-04-29 | — | — | US | disclosed |
| EP-0576357-B1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-03-05 | — | — | EP | disclosed |
| EP-0576357-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-12-29 | — | — | EP | disclosed |