Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.57 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553466 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP2C9MAOBHSD17B3CYP2D6 | |
| SCHEMBL5598564 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP2C9MAOBHSD17B3CYP2D6 | |
| SCHEMBL22596713 | 0.88 | CYP1A2 (0.79) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| SCHEMBL1556592 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| 3-Chloro-Cinnamic Acid SCHEMBL22396853 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| 3-Chloro-Cinnamic Acid SCHEMBL79592 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| 3-Chloro-Cinnamic Acid SCHEMBL79591 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| SCHEMBL1556590 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBCYP2D6MAOA | |
| SCHEMBL29538579 | 0.86 | CYP1A2 (0.73) | CYP1A2CYP2C9MAOBHSD17B3CYP2D6 | |
| SCHEMBL28739899 | 0.86 | CYP1A2 (0.73) | CYP1A2CYP2C9MAOBHSD17B3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC UNM (US) | 2016-02-11 | — | — | US | disclosed |
| US-9187397-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC.UNM | 2015-01-08 | — | — | US | disclosed |
| US-8841326-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2014-09-23 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20060276536-A1 | Cancer treatment using curcumin derivatives | STC.UNM | 2006-12-07 | — | — | US | disclosed |
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | CYP1A2 2544/4885CYP2C9 3299/4885MAOB 1674/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | CYP1A2 2544/4885CYP2C9 3299/4885MAOB 1674/4885 |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | CYP1A2 2544/4885CYP2C9 3299/4885MAOB 1674/4885 |
| US-20060276536-A1 | Cancer treatment using curcumin derivatives | BRCA1, VHL, TP53 | CYP1A2 760/4885CYP2C9 1867/4885MAOB 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.