Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556590 | 1.00 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL10981903 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL7927174 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL5598566 | 0.86 | CYP1A2 (1.00) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL22596713 | 0.86 | CYP1A2 (0.79) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL5598564 | 0.86 | CYP1A2 (1.00) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| SCHEMBL31553466 | 0.86 | CYP1A2 (1.00) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| 3-Chloro-Cinnamic Acid SCHEMBL79592 | 0.85 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| 3-Chloro-Cinnamic Acid SCHEMBL79591 | 0.85 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBMAOACYP2D6 | |
| 3-Chloro-Cinnamic Acid SCHEMBL22396853 | 0.85 | CYP1A2 (0.76) | CYP1A2CYP2C9MAOBMAOACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118144-A | Ursolic acid derivative, preparation method thereof and application thereof in glioma resistance | 中国医学科学院药物研究所 | 2025-06-10 | — | — | CN | disclosed |
| CN-114230519-B | Pleuromutilin cinnamate compounds with drug-resistant bacteria resisting activity, and synthetic method and application thereof | 西咸新区沣厚原创医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-111892539-B | Isolongifolenone caprolactam derivative and preparation method and application thereof | 南京林业大学 | 2022-03-04 | — | — | CN | disclosed |
| US-11092549-B2 | Fluorescent probes for drug permeability in gram negative bacteria | SAINT LOUIS UNIVERSITY (US) | 2021-08-17 | — | — | US | disclosed |
| EP-2491022-B1 | DIAZEPAN DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2014-12-31 | — | — | EP | disclosed |
| US-8445674-B2 | Heterocyclyl compounds | Hoffmann-La Roche Inc (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2491022-A1 | DIAZEPAM DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | F. Hoffmann-La Roche AG (CH) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011048032-A1 | DIAZEPAM DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-28 | — | — | WO | disclosed |
| US-20110092698-A1 | NOVEL HETEROCYCLYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2011-04-21 | — | — | US | disclosed |
| EP-1458720-B1 | 1,8-ANNELATED QUINOLINE DERIVATIVES SUBSTITUTED WITH CARBON-LINKED TRIAZOLES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-03-18 | — | — | EP | disclosed |
| US-5017290-A | Chromatography | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| US-4966694-A | CELLULOSE TRI-BETA-NAPHTHOATE; OPTICAL RESOLUTIONS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0156382-B1 | SEPARATION AGENT COMPRISING ACYL-OR CARBAMOYL-SUBSTITUTED POLYSACCHARIDE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4879038-A | Separation agent comprising acyl- or carbamoyl-substituted polysaccharide | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0156382-A2 | Separation agent comprising acyl-or carbamoyl-substituted polysaccharide | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4348395-A | 1,4-Dihydropyridazine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4309444-A | ANTICONVULSANT CINNAMAMIDES | BURROUGHS WELLCOME CO. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4190674-A | MUSCLE RELAXANT, OTHER HALOGENATED CINNAMIDES AS ANTICONVULSANTS | BURROUGHS WELLCOME CO. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4107320-A | Biologically active amides | BURROUGHS WELLCOME CO. (US) | 1978-08-15 | — | — | US | disclosed |
| US-3975435-A | BACTERIOSTATS | GIVAUDAN CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11092549-B2 | Fluorescent probes for drug permeability in gram negative bacteria | SLC47A2, SLC47A1, ABCB11 | CYP1A2 3956/4885CYP2C9 3109/4885MAOB 1453/4885 |
| US-20110092698-A1 | NOVEL HETEROCYCLYL COMPOUNDS | CCR2, CCR3, CCR1 | CYP1A2 2299/4885CYP2C9 719/4885MAOB 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.