Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.60 |
| ▸ | CSF1R | P07333 | 7/20 | 0.60 |
| ▸ | KDR | P35968 | 6/20 | 0.60 |
| ▸ | FLT3 | P36888 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177709 | 0.86 | PDGFRB (0.62) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2172465 | 0.78 | PDGFRB (0.62) | PDGFRBCSF1RKDRFLT3ALDH1A1 | |
| SCHEMBL2172865 | 0.76 | CSF1R (1.00) | PDGFRBCSF1RKDRFLT3 | |
| SCHEMBL2174909 | 0.74 | PDGFRB (0.82) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL4371203 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10MEN1TSHR | |
| SCHEMBL1098763 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1HTTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL2174885 | 0.72 | ALDH1A1 (0.53) | PDGFRBCSF1RKDRFLT3ALDH1A1 | |
| SCHEMBL1098455 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1HTTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL22775067 | 0.71 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL2173834 | 0.71 | EGFR (0.51) | ALDH1A1KDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |