Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL4589353 | 0.90 | SLC7A5 (0.37) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL2813584 | 0.90 | SLC7A5 (0.37) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL7562388 | 0.89 | SLC7A5 (0.40) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL28341949 | 0.89 | SLC7A5 (0.40) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL3050307 | 0.87 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL3050310 | 0.87 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL28093403 | 0.87 | SLC7A5 (0.45) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL18824897 | 0.87 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL388563 | 0.87 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL8080341 | 0.87 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186687-B2 | Compositions and methods for treatment of Psoriasis | PROCYTE CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |