Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.34 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL2813584 | 0.97 | SLC7A5 (0.37) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL5598694 | 0.90 | SLC7A5 (0.38) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL28335300 | 0.85 | SLC7A5 (0.41) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL27759487 | 0.85 | SLC7A5 (0.43) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL3050307 | 0.85 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL28093403 | 0.85 | SLC7A5 (0.45) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL3050310 | 0.85 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL8080341 | 0.85 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL3258 | 0.85 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 | |
| Histidine SCHEMBL163443 | 0.85 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255032-A1 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN | PROCYTE CORPORATION (US) | 2008-10-16 | — | — | US | disclosed |
| US-7384916-B2 | Methods and compositions for preventing and treating aging or photodamaged skin | PROCYTE CORPORATION (US) | 2008-06-10 | — | — | US | disclosed |
| EP-1765280-A1 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING HYPERPIGMENTATION OF SKIN | PROCYTE CORPORATION (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060246029-A1 | Methods and compositions for preventing and treating aging or photodamaged skin | PROCYTE CORPORATION (US) | 2006-11-02 | — | — | US | disclosed |
| US-20060018851-A1 | Methods and compositions for preventing and treating hyperpigmentation of skin | PROCYTE CORPORATION (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2006004787-A1 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING HYPERPIGMENTATION OF SKIN | PROCYTE CORPORATION (US) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246029-A1 | Methods and compositions for preventing and treating aging or photodamaged skin | RBP1, RBP4, SOD1 | SLC7A5 1876/4885CYP3A4 4549/4885CYP1A2 3205/4885 |
| US-20060018851-A1 | Methods and compositions for preventing and treating hyperpigmentation of skin | RBP1, RBP4, MC1R | SLC7A5 1015/4885CYP3A4 4639/4885CYP1A2 3145/4885 |
| US-20080255032-A1 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN | RBP1, RBP4, SOD1 | SLC7A5 1876/4885CYP3A4 4549/4885CYP1A2 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.