Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007995 | 0.80 | CA1 (0.39) | IDO1MAPK1TSHRMAOBTAAR1 | |
| SCHEMBL62723 | 0.73 | TSHR (0.67) | IDO1MAPK1TSHRHTR2AHTR2C | |
| SCHEMBL1899740 | 0.72 | MAPK1 (0.45) | IDO1L3MBTL1MAPK1TSHRHTR2A | |
| Methylamine SCHEMBL27581718 | 0.71 | TSHR (0.65) | IDO1MAPK1TSHRHTR2AHTR2C | |
| Methyl Alcohol SCHEMBL9419583 | 0.71 | TSHR (0.58) | L3MBTL1MAPK1TSHRHTR2AHTR2C | |
| SCHEMBL28126330 | 0.71 | TSHR (0.64) | IDO1MAPK1TSHRHTR2AHTR2C | |
| Fluoride SCHEMBL30661872 | 0.71 | TSHR (0.64) | IDO1MAPK1TSHRHTR2AHTR2C | |
| SCHEMBL30252943 | 0.71 | TSHR (0.64) | IDO1MAPK1TSHRHTR2AHTR2C | |
| SCHEMBL30553105 | 0.71 | TSHR (0.64) | IDO1MAPK1TSHRHTR2AHTR2C | |
| Benzene SCHEMBL8568955 | 0.71 | TSHR (0.67) | IDO1MAPK1TSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546126-B1 | PROCESS FOR PRODUCING TRIFLUOROMETHYL-SUBSTITUTED 2-ALKOXYACETOPHENONE DERIVATIVES | CENTRAL GLASS CO LTD (JP) | 2007-11-21 | — | — | EP | disclosed |