SCHEMBL62723

SCHEMBL62723

FC(F)(F)c1cccc(C(F)(F)F)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
MAPK1 P28482 1/20 0.67
ALDH1A1 P00352 2/20 0.61
CES2 O00748 1/20 0.58
MGLL Q99685 1/20 0.58
TAAR1 Q96RJ0 1/20 0.54
IDO1 P14902 2/20 0.52
HTR3E A5X5Y0 1/20 0.52
HTR3B O95264 1/20 0.52
HTR3A P46098 1/20 0.52
HTR3D Q70Z44 1/20 0.52
HTR3C Q8WXA8 1/20 0.52
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
P2RX1 P51575 1/20 0.48
KIF11 P52732 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30252943 0.97 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL28126330 0.97 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL5698952 0.97 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL30553105 0.97 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
Benzene SCHEMBL8568955 0.97 TSHR (0.67) TSHRMAPK1ALDH1A1CES2MGLL
Fluoride SCHEMBL30661872 0.97 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
Nitrogen SCHEMBL26667006 0.94 TSHR (0.61) TSHRMAPK1ALDH1A1CES2MGLL
Ethylene SCHEMBL28158839 0.94 TSHR (0.61) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL8718176 0.94 TSHR (0.63) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL13623768 0.91 TSHR (0.58) TSHRMAPK1ALDH1A1CES2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3284 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080357-A Self-adjusting sealing material and preparation method thereof 2026-05-26 CN claimed
CN-122037163-A Simple and efficient perfluoro polyether silane compound, preparation method thereof, surface treating agent and article 深圳德诚达光电材料有限公司 2026-05-15 CN claimed
WO-2026089372-A1 ION SENSOR MEMBER USING CARBON NANOTUBE COMPOSITE MATERIAL HAVING BOUND THERETO METAL-ORGANIC FRAMEWORK MODIFIED WITH ORGANIC MOLECULES, ION SENSOR, AND METHOD FOR MANUFACTURING ION SENSOR 한양대학교 산학협력단 2026-04-30 WO claimed
EP-4696679-A1 CHIRAL PYRIDINIUM SALT CARBONYL CATALYST, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Normal University (CN) 2026-02-18 EP claimed
US-20260028128-A1 ICE PROTECTION COATING AND BONDING METHODS THEREOF THE BOEING COMPANY (US) 2026-01-29 US claimed
WO-2025118357-A1 ORGANOSILICON-MODIFIED-PERFLUOROPOLYETHER-BASED UV ANTI-FINGERPRINT AGENT AND PREPARATION METHOD THEREFOR 中石油(上海)新材料研究院有限公司 2025-06-12 WO claimed
WO-2025107394-A1 PERFLUOROPOLYETHER-MODIFIED SILICON DIOXIDE MATERIAL AND PREPARATION METHOD THEREFOR 中石油(上海)新材料研究院有限公司 2025-05-30 WO claimed
CN-120025698-A Perfluoropolyether modified silicon dioxide material and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-05-23 CN claimed
CN-119955084-A Perfluoro polyether siloxane compound and preparation method thereof 漳州佳联化工有限公司 2025-05-09 CN claimed
EP-4545510-A1 METHOD FOR PRODUCING PURIFIED 1,1,2-TRIFLUOROETHANE (HFC-143), AND COMPOSITION CONTAINING HFC-143 DAIKIN INDUSTRIES, LTD. (JP) 2025-04-30 EP claimed
EP-0535597-A1 Method for preparing alpha, omega-dihydroxyperfluoroalkyl ethylmethylpolysiloxanes Dow Corning Toray Silicone Company, Limited (JP) 1993-04-07 EP claimed
US-5183839-A Protective coatings, release agents ALLIED-SIGNAL INC. (US) 1993-02-02 US claimed
US-5162577-A Chemical intermediates HOFFMANN-LA ROCHE INC. (US) 1992-11-10 US claimed
WO-1992011302-A1 FLUOROPOLYMERS AND FLUOROPOLYMER COATINGS ALLIED-SIGNAL INC. (US) 1992-07-09 WO claimed
EP-0488489-A1 Cladding material for optical fiber and method for its manufacture TORAY INDUSTRIES, INC. (JP) 1992-06-03 EP claimed
EP-0465037-A1 Solvent composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-08 EP claimed
EP-0442340-A2 Process for the preparation of an organolithium compound starting from 1,3-bis(trifluoromethyl)-benzene F. HOFFMANN-LA ROCHE AG (CH) 1991-08-21 EP claimed
US-4351975-A Process for preparing chlorinated compounds CIBA-GEIGY AG (CH) 1982-09-28 US claimed
EP-0036840-A2 Process for the production of chlorinated compounds CIBA-GEIGY AG (CH) 1981-09-30 EP claimed
US-4079090-A Preparation of trichloromethyl-trifluoro methyl-benzenes BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US claimed