SCHEMBL5599018

SCHEMBL5599018

CCCCOC(=O)N1CCCC(C(OCCN)c2cccc(F)c2-c2cccc(C)c2)C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 18/20 0.57
MITF O75030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599014 1.00 REN (0.57) RENMITF
SCHEMBL3569061 0.88 REN (0.59) REN
SCHEMBL3571302 0.88 REN (0.59) REN
SCHEMBL3569063 0.88 REN (0.59) REN
SCHEMBL3569058 0.88 REN (0.59) REN
SCHEMBL3878866 0.84 REN (0.51) REN
SCHEMBL3571858 0.81 REN (0.57) REN
SCHEMBL3571861 0.81 REN (0.57) REN
SCHEMBL3881752 0.80 REN (0.52) REN
SCHEMBL3556972 0.79 REN (0.52) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007117482-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO claimed
WO-2007117482-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO disclosed