Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | SDHA | P31040 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CALML3 | P27482 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337722 | 0.89 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6337558 | 0.88 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5592197 | 0.87 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6335788 | 0.86 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5599373 | 0.85 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6382863 | 0.85 | MAOA (0.69) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6402361 | 0.85 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6402357 | 0.85 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6382854 | 0.85 | MAOA (0.69) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5592099 | 0.85 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004032-A1 | OXAZOLIDIONES CONTAINING CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2007004032-A1 | OXAZOLIDIONES CONTAINING CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |