Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 2/20 | 0.53 |
| ▸ | PNMT | P11086 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16269628 | 0.98 | CD44 (0.51) | CD44PNMTMAOBCFDF11 | |
| Hydrochloric Acid SCHEMBL16268397 | 0.98 | CD44 (0.51) | CD44PNMTMAOBCFDF11 | |
| SCHEMBL14678265 | 0.88 | PNMT (0.49) | CD44PNMTMAOBCFDF11 | |
| SCHEMBL27746997 | 0.81 | CD44 (0.45) | CD44PNMTMAOBCFDF11 | |
| Hydrochloric Acid SCHEMBL4015918 | 0.80 | CD44 (0.44) | CD44PNMTMAOBCFDF11 | |
| SCHEMBL12942082 | 0.79 | CD44 (0.56) | CD44PNMTMAOBPRCP | |
| SCHEMBL30150923 | 0.78 | RXRB (0.43) | — | |
| SCHEMBL19212186 | 0.78 | RXRB (0.43) | — | |
| SCHEMBL20179558 | 0.77 | CD44 (0.50) | CD44PNMTMAOBPRCP | |
| SCHEMBL22096355 | 0.77 | PNMT (0.39) | CD44PNMTGAANPSR1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109182-A2 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |