Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4098966 | 0.77 | NPC1 (0.38) | ALDH1A1HTTKMT2ASMN1; SMN2MMP8 | |
| SCHEMBL2376899 | 0.65 | KMT2A (0.46) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2376897 | 0.65 | KMT2A (0.42) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL16924228 | 0.64 | MMP8 (0.50) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5696730 | 0.63 | KMT2A (0.45) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL192389 | 0.63 | HPGD (0.54) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL264305 | 0.62 | NPC1 (0.42) | ALDH1A1HTTKMT2ASMN1; SMN2MMP8 | |
| Hydrochloric Acid SCHEMBL10998190 | 0.61 | HPGD (0.53) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4388131 | 0.60 | FFAR1 (0.60) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL11791471 | 0.60 | HPGD (0.51) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |