Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.35 |
| ▸ | GNRHR | P30968 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5785441 | 0.89 | POLB (0.32) | GNRHRKCNH2ALDH1A1HPGDDPP4 | |
| SCHEMBL5599184 | 0.89 | POLB (0.32) | GNRHRKCNH2ALDH1A1HPGDDPP4 | |
| SCHEMBL5784847 | 0.87 | GNRHR (0.34) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5780824 | 0.84 | GNRHR (0.37) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5786887 | 0.83 | GNRHR (0.41) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5599768 | 0.83 | GNRHR (0.36) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5786885 | 0.82 | GNRHR (0.33) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5599977 | 0.81 | GNRHR (0.34) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5780470 | 0.81 | MAPK1 (0.37) | GNRHRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL5599124 | 0.81 | GNRHR (0.34) | GNRHRKCNH2PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |